Coronary disease & ACSCohort study
Prognosis after switching to electronic cigarettes following percutaneous coronary intervention: a Korean nationwide study
- Retrospective cohort study
- nationwide
Authors' conclusion
Among smokers who underwent PCI for coronary artery disease, switching to E-cigarette use (particularly complete transition) or quitting smoking was associated with reduced MACE risk than with continued combustible cigarette use.
Study context
- Population
- Adult smokers (≥20 years) with CAD who underwent percutaneous coronary intervention (PCI), Korean National Health Insurance database
- Participants
- 17,973 smokers
- Exposure
- Switching to E-cigarettes or quitting vs continued combustible cigarette use after PCI
- Continued combustible cigarette usersn = 8,951reference
- Switchers to E-cigarettesn = 1,694
- Successful quittersn = 7,328
- Outcome
- MACE:
- All-cause death
- Spontaneous MI
- Repeat revascularization
- Follow-up
- Median 2.4 years
Main finding
As reported in the abstract
MACE
Each group vs continued combustible cigarette usersHazard ratio (95% CI)
Switchers to E-cigarettes
0.82(0.69–0.98)
Successful quitters
0.87(0.79–0.96)
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| MACE, exclusive E-cigarette use vs dual use (subgroup of switchers) | 0.71 (0.51–0.99) | |
| 0.512Hazard ratio (log scale) |
Original publication
Prognosis after switching to electronic cigarettes following percutaneous coronary intervention: a Korean nationwide study. Eur Heart J. Published 21 October 2024. doi:10.1093/eurheartj/ehae705
Summarised from the published abstract; every number is checked against it