Acute cardiac care & resuscitation

Prognostic Implication of a Novel Right Ventricular Injury Score in Septic Patients

ESC Heart FailPublished Prospective cohort study

Authors' conclusion

The RVI score was independently related to 30 day mortality and had the potential to grade the severity of RV dysfunction in septic patients.

Study context

Population
Septic patients admitted to the ICU51 died at 30 days
Participants
327 patients
Exposure
RV injury (RVI) score 1, 2 or 3 vs RVI score 0
Outcome
Mortality
Follow-up
30 days

Main finding

As reported in the abstract

30-day mortality by RVI score
Each group vs RVI score 0Hazard ratio (95% CI)P value
RVI score 1
2.94(1.20–7.20)
P = 0.018
RVI score 2
3.20(1.28–7.98)
P = 0.013
RVI score 3
7.17(2.65–19.38)
P < 0.001

Observational data: associations, not effects.

Further findings

30-day mortality by individual right ventricular (RV) indices

HR (95% CI)P value
RV dilationMultivariate Cox regression2.19 (1.19–4.01)P = 0.011
RVSDMultivariate Cox regression2.25 (1.23–4.13)P = 0.009
RV-PA decouplingMultivariate Cox regression2.08 (1.19–3.65)P = 0.011

Prevalence of RV abnormalities

RV dilation
18.0%
RVSD
35.8%
RV-PA decoupling
21.4%
  • Appreciable overlap

Original publication

Prognostic Implication of a Novel Right Ventricular Injury Score in Septic Patients. ESC Heart Fail. Published 22 January 2023. doi:10.1002/ehf2.14289

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