Heart failure & cardiomyopathiesCohort study
Prognostic Implications and Global Perspectives of Atrial Fibrillation in Patients Hospitalized for Heart Failure
- Prospective registry cohort study
- multicentre
- 44 countries
Authors' conclusion
In a global cohort of patients hospitalized for HF, permutations of prior HF, prior AF, and AF as presenting rhythm differentiate outcome. History of prior HF influences the prognostic implications of AF in patients hospitalized for HF.
Study context
- Population
- Patients hospitalized for acute heart failure (HF) in 44 countries over 6 continents (REPORT-HF)
- Participants
- 13,401 patients
- Exposure
- Permutations of prior HF, prior atrial fibrillation (AF) and AF as presenting rhythm
- Outcome
- All-cause mortality
- Follow-up
- 1 year
Main finding
As reported in the abstract
1-year all-cause mortality
Each group vs no prior HF, no prior AF, sinus rhythmAdjusted hazard ratio (95% CI)P value
Prior HF, prior AF, presenting in AF
1.54(1.34–1.78)
P < 0.001Prior HF, no prior AF, presenting in AF
1.51(1.20–1.90)
P < 0.001Observational data: associations, not effects.
Further findings
AF prevalence (prior or newly detected) at HF admission
- AF prevalence, varying by LVEF and race subgroups
- 39%
- Prior HF
- 58%
Original publication
Prognostic Implications and Global Perspectives of Atrial Fibrillation in Patients Hospitalized for Heart Failure. JACC Heart Fail. Published 5 February 2025. doi:10.1016/j.jchf.2024.11.009
Summarised from the published abstract; every number is checked against it