Heart failure & cardiomyopathies
Prognostic Implications of Clinical and Imaging Diagnostic Criteria for Myocarditis
Authors' conclusion
In a real-world cohort of patients with possible myocarditis, diagnosis was reached in most patients using ESC criteria whereas only approximately one-quarter of patients reached a diagnosis with LLC.
Study context
- Population
- Patients with clinically suspected myocarditis referred for CMR, without prior cardiomyopathy or alternative diagnosis
- Participants
- 938 / 299 / 356 / 216 / 77
- Exposure
- European Society of Cardiology (ESC) criteria vs updated Lake-Louise criteria vs AHA probable acute myocarditis vs expert consensus acute and complicated myocarditis criteria
- ESC criterian = 938
- Lake-Louise criteria (LLC)n = 299
- Probable acute myocarditis (pAM)n = 356
- Acute myocarditis (AM)n = 216
- Complicated myocarditis (CM)n = 77
- Outcome
- Composite of:
- HF hospitalisation
- Recurrent myocarditis
- Sustained VT
- Death
- Follow-up
- Median 3.4 years
Methodological details2 centres, consecutive patients
- 2 centres
- Consecutive patients
Main finding
As reported in the abstract
Composite outcome events
LLC
6.6%
annualized event rate
HRadjusted (95% CI)P value
ESC criteria
3.87(1.22–12.2)
P = 0.021LLC
2.53(1.83–3.49)
P < 0.001- Adverse events, all patients
- 161 patients (15.3%)
- Annualized event rate with negative ESC criteria
- 0.7%
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Prognostic Implications of Clinical and Imaging Diagnostic Criteria for Myocarditis. J Am Coll Cardiol. Published 8 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →