Valvular & structural heart diseaseCohort study

Prognostic Implications of Residual Tricuspid Regurgitation Grading After Transcatheter Tricuspid Valve Repair

JACC Cardiovasc IntervPublished

  • Registry cohort study

Authors' conclusion

The moderate residual TR group was heterogeneous and encompassed patients with markedly different clinical outcomes. Refining TR grade classification with a more granular 4-grade scheme improved outcome prediction.

Study context

Population
Patients with severe isolated functional tricuspid regurgitation (TR) who underwent transcatheter tricuspid valve (TTV) repair in TRIGISTRY
Exposure
Residual TR grades after TTV repair
  • Moderaten = 319
  • Mild to moderaten = 201
  • Moderate to severen = 118
Outcome
Survival by residual TR severity at discharge
Follow-up
2 years

Main finding

As reported in the abstract

2-year adjusted survival by residual TR grade at discharge

None/mild vs None/mild: P = 0.0001 · None/mild vs None/mild: P = 0.001 · Moderate to severe vs Mild to moderate: P = 0.006 · None/mild vs Mild to moderate: P = 0.67 · Moderate to severe vs Severe: P = 0.96

Observational data: associations, not effects.

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Prognostic Implications of Residual Tricuspid Regurgitation Grading After Transcatheter Tricuspid Valve Repair. JACC Cardiovasc Interv. Published 16 May 2024. doi:10.1016/j.jcin.2024.04.023

Summarised from the published abstract; every number is checked against it