Coronary disease & ACSCohort study
Prognostic Role of Early Cardiac Magnetic Resonance in Myocardial Infarction With Nonobstructive Coronary Arteries
- Prospective cohort study
Cardiac magnetic resonance (CMR) performed on average 4.8 ± 1.5 days from acute presentation
Authors' conclusion
In MINOCA with early CMR execution, the %LGE and abnormal T2 mapping values were identified as independent predictors of adverse cardiac events at ∼3.0 years of follow-up.
Study context
- Population
- Myocardial infarction with nonobstructive coronary arteries (MINOCA) patients with early CMR, excluding acute myocarditis, takotsubo, cardiomyopathies and other nonischemic etiologies, January 2017 to October 2021437 assessed
- Participants
- 198 patients
- Exposure
- CMR phenotypes: Late gadolinium enhancement (LGE)+/M+ vs LGE-/M+ vs LGE-/M-
- LGE+/M+n = 116
- Outcome
- MACE
- Follow-up
- Mean 33.7 ± 12.0 months
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Independent predictors of MACE (multivariable Cox regression) — %LGE vs LGE-/M- | 1.123 (1.064–1.185) | P < 0.001 | |
| Independent predictors of MACE (multivariable Cox regression) — T2 mapping values vs LGE-/M- | 1.190 (1.145–1.237) | P = 0.001 | |
| 0.512Hazard ratio (log scale) |
Independent predictors of major adverse cardiovascular events (MACE) (multivariable Cox regression)
- Extension of myocardial damage at CMR significantly greater in patients who developed MACE
Original publication
Prognostic Role of Early Cardiac Magnetic Resonance in Myocardial Infarction With Nonobstructive Coronary Arteries. JACC Cardiovasc Imaging. Published 19 July 2023. doi:10.1016/j.jcmg.2023.05.016
Summarised from the published abstract; every number is checked against it