Heart failure & cardiomyopathies
Prognostic value of functional tricuspid regurgitation quantified by cardiac magnetic resonance in heart failure
Main finding · All-cause death or HF hospitalization, per 10% increase in TR fractionResult — go to the resultHazard ratio 1.49 95% CI 1.29–1.73Authors' conclusion
CMR-quantified measures of TR were independently associated with adverse clinical outcomes in patients with HFrEF.
Study context
- Population
- Patients with heart failure with reduced ejection fraction (HFrEF) who underwent cardiac magnetic resonance (CMR) (primary tricuspid regurgitation (TR), acute HF or planned cardiac surgery excluded)62 primary outcomes
- Participants
- 262 patients
- Exposure
- Higher vs lower CMR-quantified TR fraction
- Outcome
- Composite of:
- All-cause death
- Hospitalization for HF
- Follow-up
- Median 921 days
Main finding
As reported in the abstract
All-cause death or HF hospitalization, per 10% increase in TR fraction
Hazard ratio
1.49
95% CI 1.29–1.73
P < 0.001
10% increase in TR fraction
HR 1.49 (95% CI 1.29–1.73); P < 0.001
Per 10% increase in TR fraction, as printed
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Renal outcome (eGFR decrease ≥50% or progression to end-stage renal disease), per 10% increase in TR fractionCox regression; 48 renal outcomes | 1.31 (1.12–1.55) | P = 0.001 | |
| 0.512Hazard ratio (log scale) |
Renal outcome (eGFR decrease ≥50% or progression to end-stage renal disease), per 10% increase in TR fraction
- Higher TR fractions showed worse renal outcomes (Kaplan-Meier)
Original publication
Prognostic value of functional tricuspid regurgitation quantified by cardiac magnetic resonance in heart failure. Eur Heart J Cardiovasc Imaging. Published 17 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →