Prognostic value of liver biomarker scores for risk stratification in adults with Fontan palliation
Authors' conclusion
These data support the use of average liver biomarker scores for risk stratification in the setting of Fontan associated liver disease (FALD).
Study context
- Population
- Adults with Fontan palliation with ≥3 consecutive assessments of complete blood count and comprehensive metabolic panel
- Participants
- 344 adults
- Exposure
- Average vs baseline (single) liver biomarker scores and multiparametric cirrhosis diagnosis
- Outcome
- Death/transplant (prognostic value of MELD-XI, FIB-4 and APRI scores)
Main finding
As reported in the abstract
Average MELD-XI score (mean ± SD)
12.5 ± 4.1
Average FIB-4 score (mean ± SD)
1.19 ± 0.81
Average APRI score (mean ± SD)
0.61 ± 0.46
Observational data: associations, not effects.
Original publication
Prognostic value of liver biomarker scores for risk stratification in adults with Fontan palliation. Am Heart J. Published 27 June 2025. doi:10.
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