Valvular & structural heart diseaseTrial design

Progression of bicuspid-related aortopathy in patients undergoing transcatheter aortic valve implantation: Rationale and design of the international, multicenter PROSPERO-TAVI registry

Am Heart JPublished

  • investigator-initiated, multicenter, observational, ambi-spective registry
  • international
  • consecutive bicuspid aortic valve (BAV) patients

Study context

Population
Patients with native bicuspid aortic valve who underwent transcatheter aortic valve implantation (TAVI) for severe aortic stenosis between January 2018 and December 2019 with available preprocedural computed tomography angiography (CTA) assessment
Primary endpoint
Progression of BAV-associated aortopathy
Follow-up
At

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Progression of bicuspid-related aortopathy in patients undergoing transcatheter aortic valve implantation: Rationale and design of the international, multicenter PROSPERO-TAVI registry. Am Heart J. Published 27 May 2026. doi:10.1016/j.ahj.2026.107494

Summarised from the published abstract; every number is checked against it