Heart failure & cardiomyopathies

Electronic health record alerts for management of heart failure with reduced ejection fraction in hospitalized patients: the PROMPT-AHF trial

Eur Heart JPublished Randomised controlled trial

Primary resultResult — go to the resultAdjusted relative risk 0.95 CI 0.81–1.12

Authors' conclusion

A real-time, targeted, and tailored EHR-based alert system for AHF did not lead to a higher number of overall GDMT prescriptions at discharge.

Study context

Population
Patients hospitalized for acute heart failure, automatically enrolled 48 h after admission
Participants
1,012 patients
Comparison
Electronic health record (EHR) alert vs no alert
Primary endpoint
Increase in the number of GDMT prescriptions at discharge
Follow-up
Discharge
Methodological detailspragmatic, multicentre, EHR-based
  • Pragmatic
  • Multicentre
  • EHR-based

Primary result

As reported in the abstract

Adjusted relative risk

0.95

CI 0.81–1.12

P = 0.99

By group

Alert vs No alert
adjusted RR 0.95 (CI 0.81–1.12); P = 0.99

Further findings

OutcomeAdjusted RR (CI)P value
Increase in MRA1.54 (1.10–2.16)P = 0.01

On all four pillars of guideline-directed medical therapies (GDMT) at discharge

Patients on all four GDMT pillars
11.2%

Original publication

Electronic health record alerts for management of heart failure with reduced ejection fraction in hospitalized patients: the PROMPT-AHF trial. Eur Heart J. Published 31 August 2023. doi:10.1093/eurheartj/ehad512

Summarised from the published abstract; every number is checked against it

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