HypertensionCohort study
Prospective associations of daily step count and stepping intensity with overall and type-specific major adverse cardiovascular events in people with hypertension
- Prospective cohort study
- UK Biobank accelerometry sub-study
- wrist-worn accelerometer for 7 days
Authors' conclusion
Incremental 1000-step increases in daily step count, up to 10 000 steps/day, were associated with substantially lower MACE risk in adults with hypertension, particularly when accrued at a higher stepping intensity.
Study context
- Population
- Adults with established hypertension, UK Biobank accelerometry sub-study
- Participants
- 36,192 adults
- Exposure
- Per 1000-step increase in daily step count
- Outcome
- MACE:
- CV mortality
- HF
- MI
- Stroke
- Follow-up
- 7.8 years
Main finding
As reported in the abstract
Lower risk of MACE per 1000-step increase
17.1% (95% CI: 10.2-23.2)
Lower risk of heart failure (HF) per 1000-step increase
22.4% (95% CI: 11.0-31.7)
Lower risk of myocardial infarction (MI) per 1000-step increase
9.3% (95% CI: −2.8 to 19.6)
Lower risk of stroke per 1000-step increase
24.5% (95% CI: 5.3-39.0)
Observational data: associations, not effects.
Further findings
Comparison with people without hypertension
- Associations comparable with vs without hypertension for MACE, HF and stroke; lower magnitude for MI
Original publication
Summarised from the published abstract; every number is checked against it