Coronary disease & ACSCohort study
Psychosocial Factors of Women Presenting With Myocardial Infarction With or Without Obstructive Coronary Arteries
- Prospective cohort study
- multicentre
Authors' conclusion
MINOCA patients were less likely to report high stress compared with MI-CAD patients, but the frequency of elevated depressive symptoms did not differ between the 2 groups.
Study context
- Population
- Women with myocardial infarction (MI)
- Participants
- 172 vs 314
- Exposure
- Myocardial infarction with nonobstructive coronary arteries (MINOCA) vs MI-CAD
- MINOCAn = 172
- MI-CADn = 314reference
- Outcome
- High perceived stress (Perceived Stress Scale-4 ≥6) and elevated depressive symptoms (Patient Health Questionnaire-2 ≥2)
- Follow-up
- At MI (baseline) and 2 months
Main finding
As reported in the abstract
High stress (Perceived Stress Scale-4 ≥6) · At time of MI
P = 0.021
Observational data: associations, not effects.
Further findings
High stress (Perceived Stress Scale-4 ≥6) · 2 months post-MI
P = 0.019
Elevated depressive symptoms (Patient Health Questionnaire-2 ≥2) · time of MI
- No difference between MINOCA and MI-CAD (36% vs 43%)
- P = 0.229
Elevated depressive symptoms (Patient Health Questionnaire-2 ≥2) · 2 months post-MI
- No difference between MINOCA and MI-CAD (39% vs 40%)
- P = 0.999
Rate of 2-month decline in stress and depression scores
- No differences between groups
Original publication
Psychosocial Factors of Women Presenting With Myocardial Infarction With or Without Obstructive Coronary Arteries. J Am Coll Cardiol. Published 24 October 2023. doi:10.1016/j.jacc.2023.08.028
Summarised from the published abstract; every number is checked against it