Arrhythmias & electrophysiologyResearch article
Pulmonary vein and posterior wall isolation using the circular, multielectrode catheter for treatment of atrial fibrillation: Acute and long-term outcomes from the Pulsed-Field Ablation for pulmonary vein isolation (PVI) Using PulseSelect With Adjunct Posterior Wall Isolation trial
- retrospectively analyzed the outcomes of consecutive patients
- real-world
Authors' conclusion
These real-world results demonstrate that PVI with/without PWI using the circular, multielectrode array PFA catheter is safe, feasible, and effective in patients with symptomatic PAF and PsAF with a low risk of complications, including hemolysis.
Study context
- Population
- Patients with symptomatic paroxysmal AF (PAF)/persistent AF (PsAF) who underwent catheter ablation using the circular, multielectrode pulsed-field ablation (PFA) catheterage 69 ± 11 years, 62% male, 61% PAF
- Participants
- 178 patients
- Comparison
- PVI vs PVI + posterior wall isolation (PWI)
- PVI + PWIn = 172
Main finding
As reported in the abstract
Acute PVI
Acute PVI achieved
100% (n = 178)
Further findings
Freedom from recurrent atrial arrhythmia · 1 year
Procedural characteristics
- PFA applications
- 62 ± 17
- procedure time
- 66 ± 11 minutes
- fluoroscopy time
- 14 ± 5 minutes
- patients who received PVI + PWI
- 96.6% (n = 172)
Safety
Adverse events
- adverse events
- 4 (2.2%)
- minor adverse events
- 2
Serum total bilirubin increase · 2 hours after ablation
- increase in serum total bilirubin
- 1.01 mg/dL; 95% confidence interval, 0.84-1.17; P < .001
- All changes in biomarkers resolved spontaneously within 48-72 hours without clinical sequelae
Stage 1 acute kidney injury
- stage 1 acute kidney injury in patient with a history of chronic kidney disease
- 1 patient
Original publication
Pulmonary vein and posterior wall isolation using the circular, multielectrode catheter for treatment of atrial fibrillation: Acute and long-term outcomes from the Pulsed-Field Ablation for PVI Using PulseSelect With Adjunct Posterior Wall Isolation trial. Heart Rhythm. Published 6 June 2026. doi:10.1016/j.hrthm.2026.06.002
Summarised from the published abstract; every number is checked against it