Valvular & structural heart disease
Quality of Life 5 Years Following Transfemoral Transcatheter Aortic Valve Replacement (TAVR) or Surgical Aortic Valve Replacement (SAVR) in Intermediate Risk Patients
Authors' conclusion
In intermediate-risk AS patients, both transfemoral TAVR and SAVR resulted in comparable and durable health status benefits to 5 years.
Study context
- Population
- Intermediate-risk patients with symptomatic severe aortic stenosis (AS)included in analysis
- Participants
- 1,584 patients
- Comparison
- Transfemoral TAVR vs SAVR
- TAVRn = 805
- SAVRn = 779reference
- Primary endpoint
- Disease-specific health status (KCCQ), change from baseline
- Follow-up
- Through 5 years
Primary result
As reported in the abstract
Mean change in KCCQ-OS from baseline · 5 years
TAVR
15.4
mean change · SD 25.1
SAVR
14.3
mean change · SD 24.2
Further findings
Mean change
| Outcome | TAVR | SAVR |
|---|---|---|
| Mean change in KCCQ-OS from baseline · 1 year | 20.5 (SD 22.4) | 20.5 (SD 22.2) |
Mean change in KCCQ-OS from baseline · 1 year
- Health status improved more rapidly after TAVR vs SAVR
Kansas City Cardiomyopathy Questionnaire (KCCQ) subscales
- Similar findings; substantial attenuation of benefit in physical limitation subscale over time in both groups
Original publication
Quality of Life 5 Years Following Transfemoral TAVR or SAVR in Intermediate Risk Patients. JACC Cardiovasc Interv. Published 22 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →