Coronary disease & ACS

Quantitative flow ratio versus fractional flow reserve for guiding percutaneous coronary intervention: design and rationale of the randomised FAVOR III Europe Japan trial

EuroInterventionPublished Design and rationale of a randomised controlled trial

Study context

Population
Patients with stable angina and intermediate coronary stenosis, or an indication for functional assessment of ≥1 non-culprit lesion after acute MI2,000 planned
Planned comparison
Quantitative flow ratio (QFR)-based vs standard fractional flow reserve (FFR)-based diagnostic strategy
Primary endpoint
MACE:
  • All-cause mortality
  • Any MI
  • Any unplanned coronary revascularisation
Follow-up
12 months
Methodological detailsFAVOR III Europe Japan, investigator-initiated, non-inferiority, clinical outcome, up to 40 international centres
  • FAVOR III Europe Japan
  • Investigator-initiated
  • Non-inferiority
  • Clinical outcome
  • Up to 40 international centres

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Quantitative flow ratio versus fractional flow reserve for guiding percutaneous coronary intervention: design and rationale of the randomised FAVOR III Europe Japan trial. EuroIntervention. Published 3 April 2023. doi:10.4244/eij-d-21-00214

Summarised from the published abstract; every number is checked against it

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