Valvular & structural heart disease
Quantitative tricuspid regurgitation assessment by cardiac magnetic resonance: novel insights
Authors' conclusion
In this all-comers TR cohort, CMR quantification of TR using TRF associated with guideline-based criteria for echocardiographic diagnosis of severe TR. RV remodelling objective right-sided HF signs/symptoms already occurred at TRF thresholds ≥20%, supporting the physiological consequences.
Study context
- Population
- All-comers TR cohort: patients with prospective comprehensive CMR with TR assessment
- Participants
- 335 participants
- Exposure
- CMR quantitation of TR severity (TRF) and its association with clinical and physiological consequences
- Outcome
- TRF
Main finding
As reported in the abstract
Median TRF
21%
13–33%
Observational data: associations, not effects.
Further findings
RV-EDVi
| Outcome | TRF > 40% | TRF 21-40% | TRF ≤ 20% |
|---|---|---|---|
| L-ECV | 36% (range 32–39%) | 31% (range 28–34%) | 27% (range 26–30%) |
| TAPSE/PASP ratio | 0.38 (range 0.32–0.46) | 0.53 (range 0.34–0.68) | 0.69 (range 0.52–0.87) |
| TRISCORE | 5 (range 3–7) | 2 (range 1–3) | 1 (range 0–2) |
- L-ECV: P < 0.001
- RV-EDVi: P < 0.001
- TAPSE/PASP ratio: P < 0.001
- TRISCORE: P < 0.001
Number of guideline-based echocardiographic signs of severe TR
- Strongly associated with TRF
- P < 0.001
Original publication
Quantitative tricuspid regurgitation assessment by cardiac magnetic resonance: novel insights. Eur Heart J Cardiovasc Imaging. Published 15 October 2025. doi:10.
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