Valvular & structural heart disease
The R-wave amplitude in V1 on baseline electrocardiogram correlates with the occurrence of high-degree atrioventricular block following left bundle branch block after transcatheter aortic valve replacement
Authors' conclusion
The R-wave amplitude in lead V1 during baseline ECG in patients with normal QRS duration may predict the occurrence of high-degree AVB following new LBBB after TAVR.
Study context
- Population
- Patients with normal QRS duration who developed new left bundle branch block (LBBB) after transcatheter aortic valve replacement (TAVR)117 analysed
- Participants
- 720 patients
- Exposure
- Group 1 vs Group 2
- Group 1n = 14
- Group 2n = 103reference
- Outcome
- Association of baseline R-wave amplitude in V1 with high-degree AVB following LBBB
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
R-wave amplitude in V1 · baseline (pre-TAVR)
P = 0.0316
- ROC cutoff for R-wave amplitude pre-TAVR
- 0.03 mV
- AUC
- 0.7219 (P = 0.0002)
Observational data: associations, not effects.
Further findings
Left anterior hemiblock · not statistically significant
P = 0.156
Baseline demographics, procedural characteristics, PR interval, QRS duration, QRS axis
- No significant differences between groups
Original publication
The R-wave amplitude in V1 on baseline electrocardiogram correlates with the occurrence of high-degree atrioventricular block following left bundle branch block after transcatheter aortic valve replacement. Europace. Published 20 March 2023. doi:10.
Summarised from the published abstract; every number is checked against it