Radial-Artery or Saphenous-Vein Grafts in Coronary-Artery Bypass Surgery
Pooled resultResult — go to the resultHazard ratio 0.67 95% CI 0.49–0.90Authors' conclusion
As compared with the use of saphenous-vein grafts, the use of radial-artery grafts for CABG resulted in a lower rate of adverse cardiac events and a higher rate of patency at 5 years of follow-up.
Study context
- Population
- Patients undergoing coronary-artery bypass grafting (CABG) in 6 RCTs
- Participants
- 1,036 patients6 RCTs
- Comparison
- Radial-artery grafts vs saphenous-vein grafts for CABG
- Radial-artery graftsn = 534
- Saphenous-vein graftsn = 502reference
- Outcome
- Composite of:
- Death
- MI
- Repeat revascularization
- Follow-up
- Mean 60±30 months
Methodological detailsmixed-effects Cox regression
- Mixed-effects Cox regression
Pooled result
As reported in the abstract
Hazard ratio
0.67
95% CI 0.49–0.90
P = 0.01
Radial-artery graftsvs Saphenous-vein grafts
HR 0.67 (95% CI 0.49–0.90); P = 0.01
Further pooled results
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Graft occlusion on follow-up angiography · mean follow-up 50±30 months | 0.44 (0.28–0.70) | P < 0.001 | |
| MINominally lower | 0.72 (0.53–0.99) | P = 0.04 | |
| Repeat revascularization | 0.50 (0.40–0.63) | P < 0.001 | |
| Death from any cause | 0.90 (0.59–1.41) | P = 0.68 | |
| 0.20.5125Hazard ratio (log scale) |
Original publication
Radial-Artery or Saphenous-Vein Grafts in Coronary-Artery Bypass Surgery. N Engl J Med. Published 30 April 2018. doi:10.
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