Arrhythmias & electrophysiologyTrial design
Rationale and design of a multicenter randomized trial of adjunctive non-pulmonary vein trigger ablation in persistent atrial fibrillation: The EXPORT trial
- multicenter, prospective, superiority, single-blinded, blinded-endpoint, clinical trial
- randomized
- rationale and design
Study context
- Population
- Participants with persistent atrial fibrillation (AF) refractory to AAD therapy undergoing first-time AF ablationestimated total sample size · pulmonary vein (PV) isolation with non-PV trigger provocation, mapping, and ablation 215 · PV isolation alone 215
- Participants
- 430 participants
- Planned comparison
- systematic non-PV trigger ablation over PV isolation alone
- PV isolation with non-PV trigger provocation, mapping, and ablationn = 215
- PV isolation alonen = 215
- Primary endpoint
- any documented atrial arrhythmia lasting ≥30 s after a 3-month blanking period following ablation with or without the use of AADs
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Rationale and design of a multicenter randomized trial of adjunctive non-pulmonary vein trigger ablation in persistent atrial fibrillation: The EXPORT trial. Am Heart J. Published 1 October 2026. doi:10.1016/j.ahj.2026.107624
Summarised from the published abstract; every number is checked against it