Arrhythmias & electrophysiologyCohort study
Real-world assessment of multipolar and point-by-point mapping for premature ventricular contraction ablation
- Retrospective cohort study
- international
- multicentre
- 10 hospital centres
- consecutive patients
Authors' conclusion
The acute and midterm efficacies of PVC ablation are high with both multipolar and PbP mapping, although the former allows for quicker procedures and may potentially improve the outcomes of left-sided PVC ablation.
Study context
- Population
- Consecutive patients referred for premature ventricular contraction (PVC) ablation, January 2017 to December 2021592 received activation mapping
- Participants
- 698 patients
- Exposure
- Multipolar vs point-by-point mapping for PVC ablation
- Multipolarn = 248
- Point-by-point (PbP)n = 344reference
- Outcome
- Acute (procedural) and midterm efficacy of PVC ablation
Main finding
As reported in the abstract
Acute success and midterm efficacy
Acute success
Midterm efficacy
Observational data: associations, not effects.
Further findings
Mapping time
Procedure time
| Outcome | Multipolar | PbP | adjusted OR (95% CI) | P value | |
|---|---|---|---|---|---|
| Midterm efficacy, left-sided PVC ablation (subgroup) · multipolar mapping independent predictor of success | 80.7% | 69.5% | 2.231 (1.476–5.108) | P = 0.02 | |
| 0.20.5125Adjusted odds ratio (log scale) |
| Outcome | Multipolar | PbP | Estimate | P value |
|---|---|---|---|---|
| Activation points | 432 (IQR 217–843) | 95 (IQR 42–185) |
- Activation points: P < 0.001
- Mapping time: P < 0.001
- Procedure time: P < 0.001
- Midterm efficacy, left-sided PVC ablation (subgroup): P = 0.04
Safety
Adverse events
- Adverse events: P = 0.24
Original publication
Real-world assessment of multipolar and point-by-point mapping for premature ventricular contraction ablation. Europace. Published 31 May 2024. doi:10.1093/europace/euae148
Summarised from the published abstract; every number is checked against it