Arrhythmias & electrophysiology
Repolarization and Activation Mapping in Ventricular Tachycardia Ablation: The REDEEM Study
Authors' conclusion
The REDEEM method is feasible and shows anatomical associations with VT isthmus sites. This hypothesis-generating study provides mechanistic insights that warrant prospective validation.
Study context
- Population
- Patients undergoing ventricular tachycardia (VT) ablationpatients with 20 mapped VTs
- Participants
- 20 patients
- Exposure
- Repolarization cliffs and deceleration zones (DZs) against VT isthmus sites
Methodological details2 centers
- 2 centers
Main finding
As reported in the abstract
VT exit site or any boundary of the diastolic channel overlap
Overlapped with a repolarization cliff
20 VTs
100.0%
Overlapped with a DZ
14 VTs
70.0%
Observational data: associations, not effects.
Further findings
VT entrance site overlap
- Overlapped with a repolarization cliff
- 2 VTs (10.0%)
- Overlapped with a DZ
- 18 VTs (90.0%)
Mid-isthmus location
- In an area connecting a DZ with a repolarization cliff
- 19 VTs (95.0%)
Positive predictive value for any isthmus site
- Repolarization cliff
- 63.2%
- DZ
- 40.1%
Original publication
Repolarization and Activation Mapping in Ventricular Tachycardia Ablation: The REDEEM Study. JACC Clin Electrophysiol. Published 13 June 2026. doi:10.
Summarised from the published abstract; every number is checked against it