Valvular & structural heart diseaseCohort study
Redefining Transcatheter Aortic Valve Replacement (TAVR) Valve Sizing
- Retrospective cohort study
- propensity-matched comparison with VENUS-A cohort
Authors' conclusion
Multiplanar supra-annular measurement provides a comprehensive evaluation of aortic root anatomy, enabling more precise TAVR sizing for both BAV and TAV patients.
Study context
- Population
- Patients with bicuspid aortic valve (BAV) or TAV undergoing TAVR with the Venus A-Valve191 BAV, 186 TAV
- Participants
- 377 patients
- Exposure
- Multiplanar supra-annular sizing vs traditional annulus-based sizing
Main finding
As reported in the abstract
Downsizing vs annulus-based sizing
Observational data: associations, not effects.
Further findings
| Outcome | Multiplanar strategy | Annulus-based | OR (95% CI) | P value | |
|---|---|---|---|---|---|
| Valve-in-valve procedures | 3.1% | 12.2% | 3.9 (1.206–16.186) | P = 0.032 | |
| 0.050.21520Odds ratio (log scale) |
- Valve-in-valve procedures: propensity-matched cohort (n = 98 pairs)
Postoperative morphologic and biomechanical analyses (subset n = 54)
- Strong correlations between preprocedural measurements and postimplantation valve morphology and biomechanics
Original publication
Redefining TAVR Valve Sizing. JACC Cardiovasc Interv. Published 28 July 2025. doi:10.1016/j.jcin.2025.05.043
Summarised from the published abstract; every number is checked against it