Valvular & structural heart diseaseMeta-analysis

Registries on Transcatheter Edge-To-Edge Repair in Heart Failure: Current Evidence and Future Perspectives

Eur J Heart FailPublished

  • Systematic review of registries
  • PubMed, Web of Science and EMBASE searched

Authors' conclusion

Registries on TEER represent a key data source in a setting where it is difficult to conduct randomized controlled trials. However, limitations in design, patient characterization, and outcomes reporting restrain their use.

Study context

Population
Patients with heart failure (HF) receiving transcatheter edge-to-edge repair (TEER) for secondary mitral or tricuspid regurgitation26 + 6 registries
Participants
18,925 vs 1,412
Comparison
TEER in secondary mitral regurgitation (SMR) vs TEER for tricuspid regurgitation (TR)
  • TEER in SMRn = 18,925
  • TEER for TRn = 1,412

Pooled result

As reported in the abstract

Registries retrieved

SMR: 26 registries (46% prospective, 12% ongoing), total cohort

18 925

TR: 6 registries (50% retrospective, 33% ongoing), total cohort

1412

Original publication

Registries on Transcatheter Edge-To-Edge Repair in Heart Failure: Current Evidence and Future Perspectives. Eur J Heart Fail. Published 8 January 2025. doi:10.1002/ejhf.3573

Summarised from the published abstract; every number is checked against it