Relationship between 10- and 30-year PREVENT risk scores with coronary artery calcium and incident atherosclerotic cardiovascular disease: MESA
Main finding · Incident ASCVD eventsResult — go to the resultHazard ratio 2.21 95% CI 1.62–2.94Study context
- Population
- MESA participants with CAC measured by CT and calculated PREVENT risk score; mean age 62.2 years, 52.8% female, 61.5% non-White
- Participants
- 6,747 participants
- Exposure
- Low 10-year PREVENT atherosclerotic CVD (ASCVD) risk with elevated 30-year risk vs low risk by both metrics
- Outcome
- CAC (prevalent, incident, progression) and incident ASCVD by PREVENT 10-year and 30-year risk categories
Methodological detailsanalysis of the Multi-Ethnic Study of Atherosclerosis
- Analysis of the Multi-Ethnic Study of Atherosclerosis
Main finding
Incident ASCVD events
Hazard ratio
2.21
95% CI 1.62–2.94
Low 10-year/elevated 30-year riskvs Low by both metrics
HR 2.21 (95% CI 1.62–2.94)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Prevalent and incident CAC
- Higher prevalence of CAC with low 10-year but elevated 30-year risk vs low by both metrics; incident CAC followed a similar pattern
CAC progression
- CAC progression similar across risk thresholds for both risk equations
Original publication
Relationship between 10- and 30-year PREVENT risk scores with coronary artery calcium and incident atherosclerotic cardiovascular disease: MESA. Eur J Prev Cardiol. Published 17 December 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →