Arrhythmias & electrophysiology

Relationship between epicardial adipose tissue measured by computed tomography and premature ventricular complexes originating from different sites

EuropacePublished Case-control study

An erratum to this article was published (Europace, 19 May 2023 ↗)

Authors' conclusion

Higher volume and lower density of EAT were significantly associated with frequent PVCs. The RVOT-PVC patients had a higher volume ratio and a smaller density differential. The LVOT-PVCs had a lower volume ratio and the LV-PVCs showed a greater density differential.

Study context

Population
Patients undergoing radiofrequency ablation for premature ventricular complexes (PVCs)1:1 matched
Comparison
PVC patients vs matched controls; PVCs by site of origin
  • PVCsn = 136
  • Controlsn = 136reference
Outcome
Volume and density of EAT in different zones, quantified by computed tomography (CT)
Methodological details1:1 matching
  • 1:1 matching

Main finding

As reported in the abstract

PVCs: significantly higher epicardial adipose tissue (EAT) volume and lower EAT density than controls
P < 0.001
Higher LV periventricular EAT volume (LV-EATv) proportion in LVOT-PVCs and LV-PVCs
P < 0.05
Higher RV periventricular EAT volume (RV-EATv) proportion in RVOT-PVCs and LVOT-PVCs
P < 0.05
RVOT-PVCs: higher volume ratio and smaller density differential
P < 0.05
LVOT-PVCs: lower volume ratio; LV-PVCs: greater density differential
P < 0.05

Observational data: associations, not effects.

Original publication

Relationship between epicardial adipose tissue measured by computed tomography and premature ventricular complexes originating from different sites. Europace. Published 21 April 2023. doi:10.1093/europace/euad102

Composed by AI from the published abstract and checked against it. How Briefs are made →

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