Arrhythmias & electrophysiology
Relationship between epicardial adipose tissue measured by computed tomography and premature ventricular complexes originating from different sites
An erratum to this article was published (Europace, 19 May 2023 ↗)
Authors' conclusion
Higher volume and lower density of EAT were significantly associated with frequent PVCs. The RVOT-PVC patients had a higher volume ratio and a smaller density differential. The LVOT-PVCs had a lower volume ratio and the LV-PVCs showed a greater density differential.
Study context
- Population
- Patients undergoing radiofrequency ablation for premature ventricular complexes (PVCs)1:1 matched
- Comparison
- PVC patients vs matched controls; PVCs by site of origin
- PVCsn = 136
- Controlsn = 136reference
- Outcome
- Volume and density of EAT in different zones, quantified by computed tomography (CT)
Methodological details1:1 matching
- 1:1 matching
Main finding
As reported in the abstract
- PVCs: significantly higher epicardial adipose tissue (EAT) volume and lower EAT density than controls
- P < 0.001
- Higher LV periventricular EAT volume (LV-EATv) proportion in LVOT-PVCs and LV-PVCs
- P < 0.05
- Higher RV periventricular EAT volume (RV-EATv) proportion in RVOT-PVCs and LVOT-PVCs
- P < 0.05
- RVOT-PVCs: higher volume ratio and smaller density differential
- P < 0.05
- LVOT-PVCs: lower volume ratio; LV-PVCs: greater density differential
- P < 0.05
Observational data: associations, not effects.
Original publication
Relationship between epicardial adipose tissue measured by computed tomography and premature ventricular complexes originating from different sites. Europace. Published 21 April 2023. doi:10. 1093/ europace/ euad102
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