Heart failure & cardiomyopathies
Relationship Between Waist-to-Height Ratio and Heart Failure Outcome: A Single-Centre Prospective Cohort Study
Main finding · All-cause mortalityResult — go to the resultHazard ratio 1.83 CI 1.30–2.58Authors' conclusion
The obesity paradox, as delineated by WHtR, is observed in patients with HFrEF, yet absent in those with HFpEF.
Study context
- Population
- Patients with heart failure (HF) across ejection fraction (EF) categories, tertiary hospital in China
- Participants
- 859 patients
- Exposure
- Low waist-to-height ratio (WHtR) vs high WHtR
- Outcome
- All-cause mortality
- Follow-up
- 48 months
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Hazard ratio
1.83
CI 1.30–2.58
Low WHtR vs High WHtR
HR 1.83 (CI 1.30–2.58)
- Total deaths at end of follow-up
- 149 (18.9%)
Observational data: associations, not effects.
Further findings
| Outcome | HR | |
|---|---|---|
| CV death | 1.96 (CI 1.34–2.88) | |
| Mortality in HFrEF (subgroup)HFrEF/low WHtR vs HFrEF/high WHtR · all-cause mortality | 2.31 (95% CI 1.24–4.30) | |
| Mortality in HFrEF (subgroup)HFrEF/low WHtR vs HFrEF/high WHtR · HF mortality | 3.52 (95% CI 2.92–8.80) | |
| Mortality in HFrEF (subgroup)HFrEF/low WHtR vs HFrEF/high WHtR · noncardiovascular mortality | 4.59 (95% CI 1.19–17.76) | |
| 0.050.21520Hazard ratio (log scale) |
Noncardiovascular mortality and rehospitalization
- No significant difference between the two groups
All-cause and CV mortality in HF with preserved EF (subgroup)
- WHtR has a negligible effect on risk
Original publication
Relationship Between Waist-to-Height Ratio and Heart Failure Outcome: A Single-Centre Prospective Cohort Study. ESC Heart Fail. Published 17 September 2024. doi:10.
Summarised from the published abstract; every number is checked against it