Prevention & lipidsCohort study
Remnant cholesterol, plasma triglycerides, and risk of cardiovascular disease events in young adults: a prospective cohort study
- Prospective cohort study
- registry linkage
Authors' conclusion
Already at 31 years of age, higher concentrations of remnant cholesterol and plasma triglycerides were associated with increased risk of premature CVD events.
Study context
- Population
- All 30-year-old inhabitants of Oslo, Norway, invited to the Oslo Health Study in 2000median age 31 years, 56% women
- Participants
- 5,939 participants
- Exposure
- Remnant cholesterol and plasma TG levels, with LDL-C as comparison
- Outcome
- CVD events:
- CV death
- Non-fatal MI
- Non-fatal ischaemic stroke
- Coronary revascularization
- Hospitalization for unstable angina
- Follow-up
- Median 22 years
Main finding
As reported in the abstract
CVD events
Adjusted hazard ratio (95% CI)
Remnant cholesterolper 0.5 mmol/L increase
1.3(1.1–1.5)
Plasma triglyceridesper 1 mmol increase
1.2(1.1–1.4)
LDL-Cper 1 mmol increase; comparison
1.3(1.1–1.6)
Each row per its own increment, as printed
- Cardiovascular disease (CVD) events
- 107 (1.8%)
Observational data: associations, not effects.
Original publication
Remnant cholesterol, plasma triglycerides, and risk of cardiovascular disease events in young adults: a prospective cohort study. Eur J Prev Cardiol. Published 25 February 2025. doi:10.1093/eurjpc/zwaf104
Summarised from the published abstract; every number is checked against it