HypertensionCohort study
Renal denervation increases capillary density in hypertensive patients
- Prospective cohort study
Authors' conclusion
In patients with arterial hypertension, blood pressure reduction by RDN increased retinal capillary density both 6 and 12 months after the procedure.
Study context
- Population
- Patients with uncontrolled hypertension confirmed by 24-h ambulatory BP undergoing endovascular renal denervation
- Participants
- 132 patients
- Exposure
- Before vs after endovascular renal denervation
- Outcome
- Retinal capillary density (CapA) by scanning laser Doppler flowmetry
- Follow-up
- 6 and 12 months after RDN
Main finding
As reported in the abstract
Retinal capillary density (CapA)
6 months vs Baseline: P = 0.021 · 12 months vs Baseline: P = 0.034 · 12 months vs 6 months: P = 0.097
Observational data: associations, not effects.
Further findings
| Outcome | Baseline | 6 months after RDN | 12 months after RDN |
|---|---|---|---|
| 24-h ambulatory BP | 151/88 mmHg | 143/84 mmHg | 142/82 mmHg |
- 24-h ambulatory BP: all P < 0.001
Original publication
Renal denervation increases capillary density in hypertensive patients. Eur J Prev Cardiol. Published 27 June 2025. doi:10.1093/eurjpc/zwaf387
Summarised from the published abstract; every number is checked against it