Heart failure & cardiomyopathiesMeta-analysis
Reporting Quality of Heart Failure Randomized Controlled Trials 2000–2020: Temporal Trends in Adherence to CONsolidated Standards Of Reporting Trials (CONSORT) Criteria
- Systematic review (meta-research study of reporting quality)
Authors' conclusion
The quality of reporting in HF RCTs, as measured by CONSORT adherence, has improved over time but remains suboptimal.
Study context
- Population
- Heart failure (HF) randomized controlled trials (RCTs) published in high-impact journals 2000–2020 (MEDLINE, EMBASE, CINAHL)RCTs analysed
- Participants
- 221 rcts
- Outcome
- Adherence to CONSORT 2010 update
Pooled result
As reported in the abstract
Adherence to CONSORT 2010
Mean (SD) adherence, overall (suboptimal)
69.7 [11.5]%
Criteria met
5513/7913
Temporal increase in adherence over 20 years
p < 0.001
Further pooled results
| Outcome | β (95% CI) | P value |
|---|---|---|
| Trial characteristics associated with adherence (multivariable linear regression) — Published after 2010 vs During/before 2010 | 10.17 (7.64–12.70) | P < 0.001 |
| Trial characteristics associated with adherence (multivariable linear regression) — Two-group parallel individual-level randomization vs Other (incl. multi-group or cluster) | 5.81 (2.88–8.73) | P < 0.001 |
| Trial characteristics associated with adherence (multivariable linear regression) — Multicentre vs Single-centre | 7.26 (3.25–11.27) | P < 0.001 |
Adherence to CONSORT 2010 vs original 1996 criteria (sensitivity analysis)
- No difference in adherence; similar temporal trends
Adherence vs journal impact factor
- Positive correlation
- r = 0.312; p < 0.001
Original publication
Reporting Quality of Heart Failure Randomized Controlled Trials 2000–2020: Temporal Trends in Adherence to CONSORT Criteria. Eur J Heart Fail. Published 16 April 2024. doi:10.1002/ejhf.3229
Summarised from the published abstract; every number is checked against it