Valvular & structural heart diseaseCohort study

Residual Mitral Regurgitation as a Long-Term Predictor of Mortality After Mitral TEER

JACC Cardiovasc IntervPublished

  • Registry study (5-year follow-up of the MITRA-PRO registry)

Authors' conclusion

Residual MR assessed by intraprocedural MitraScore after M-TEER independently predicts 5-year mortality.

Study context

Population
Patients after mitral transcatheter edge-to-edge repair (M-TEER)
Participants
1,491 patients
Exposure
Mild or less residual mitral regurgitation (MR) vs relevant residual MR after M-TEER
Outcome
Mortality
Follow-up
5 years

Main finding

As reported in the abstract

5-year mortality

Observational data: associations, not effects.

Further findings

5-year mortality, degenerative MR (subgroup)

5-year mortality, functional MR (subgroup)

Intraprocedural MitraScore and mortality

Relationship almost linear

Time-dependent predictors of mortality

Early risk driven by advanced disease and procedural factors; residual MR prognostic after 30 days and associated with excess long-term mortality

Original publication

Residual Mitral Regurgitation as a Long-Term Predictor of Mortality After Mitral TEER. JACC Cardiovasc Interv. Published 28 September 2026. doi:10.1016/j.jcin.2026.06.034

Summarised from the published abstract; every number is checked against it