Arrhythmias & electrophysiologyCohort study
Residual tiny pulmonary vein potentials on high-resolution mapping after pulsed field ablation predict atrial arrhythmia recurrence and poor durability of pulmonary vein isolation
- retrospective observational study
Authors' conclusion
Residual tiny PVPs detected by high-resolution mapping after PFA predict 1-year AF/AT recurrence and precede clinically significant LA-PV reconnection.
Study context
- Population
- Patients who underwent an initial ablation for atrial fibrillation (AF) using a single-shot pulsed field ablation (PFA) device and were evaluated with high-resolution mapping immediately after ablation
- Participants
- 158 patients
- Exposure
- presence of residual tiny PV potentials (PVPs)
- Residual tiny PVPsn = 48
Main finding
AF/AT recurrence · 1-year follow-up
Hazard ratio
2.68
95% CI 1.14–6.31
P = 0.024
Residual tiny PVPs vs No residual tiny PVPs
hazard ratio 2.68 (95% CI 1.14–6.31); P = 0.024
As reported in the abstract
Observational data: associations, not effects.
Further findings
Locational concordance of residual tiny PVP sites with late-phase LA-PV reconnection
- Residual tiny PVP sites concordant with late-phase LA-PV reconnection, among 15 patients undergoing repeat ablation
- 81%
Original publication
Residual tiny pulmonary vein potentials on high-resolution mapping after pulsed field ablation predict atrial arrhythmia recurrence and poor durability of pulmonary vein isolation. Heart Rhythm. Published 29 April 2026. doi:10.1016/j.hrthm.2026.04.047
Summarised from the published abstract; every number is checked against it