Valvular & structural heart diseaseCohort study
Restoration of Life Expectancy After Transcatheter Edge-to-Edge Mitral Valve Repair
- Registry-based cohort study
- relative survival analysis
- consecutive patients
Authors' conclusion
Mitral TEER in patients 80 to 89 years of age is able to restore predicted life expectancy in PMR, whereas in SMR with sustained procedural success, high RS estimates were observed.
Study context
- Population
- Consecutive transcatheter edge-to-edge repair (TEER) patients aged 60 to 89 years in the MitraSwiss registry, enrolled 2011–2018
- Participants
- 1,140 patients
- Exposure
- TEER survival vs expected survival in age-, sex- and calendar period-matched general population
- Outcome
- Survival and relative survival (RS) after TEER
- Follow-up
- 5 years
Main finding
As reported in the abstract
5-year survival and RS after TEER
| Group | 5-year survival | Relative survival (RS) |
|---|---|---|
| TEER | 59.3% (95% CI: 54.9%-63.4%) | 80.5% (95% CI: 74.6%-86.0%) |
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| Relative survival by etiology of mitral regurgitation · 5 years | PMR 91.1% (95% CI 82.5%–98.6%) · SMR 71.5% (95% CI 63.0%–79.3%) |
| Relative survival, patients 80 to 89 years of age (n = 579) | 80 to 89 years of age 93.0% (95% CI 83.3%–101.9%) |
| Relative survival in patients 80 to 89 years of age, by etiology · PMR: restoration of predicted life expectancy · SMR: with sustained procedural success | PMR 100% (95% CI 87.9%–110.7%) · SMR 90.6% (95% CI 71.3%–107.3%) |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Restoration of Life Expectancy After Transcatheter Edge-to-Edge Mitral Valve Repair. JACC Cardiovasc Interv. Published 23 August 2023. doi:10.1016/j.jcin.2023.06.014
Summarised from the published abstract; every number is checked against it