Coronary disease & ACSSecondary analysis
Restrictive Versus Liberal Transfusion in Patients With Type 1 or Type 2 Myocardial Infarction: A Prespecified Analysis of the MINT Trial
- Secondary analysis of the MINT randomised trial
- prespecified analysis
Authors' conclusion
The concern for harm with a restrictive transfusion strategy in patients with acute MI and anemia raised in the MINT primary outcome manuscript may be more apparent in patients with type 1 than type 2 MI.
Study context
- Population
- Patients with type 1 or type 2 acute myocardial infarction (MI) and anemiatype 1 MI n=1460 · Patients with type 1 1,460 · or type 2 1,955
- Comparison
- Restrictive vs liberal transfusion strategy, by MI type
- Primary endpoint
- Death or MI
- Follow-up
- 30 days
Primary result
As reported in the abstract
Death or MI, by MI type
Restrictive vs LiberalRelative risk (95% CI)
type 1 MI
1.32(1.04–1.67)
type 2 MI
1.05(0.85–1.29)
Further findings
Death or MI, overall by MI type · 30 days
- Type 1 MI
- 16%
- Type 2 MI
- 15.4%
Original publication
Restrictive Versus Liberal Transfusion in Patients With Type 1 or Type 2 Myocardial Infarction: A Prespecified Analysis of the MINT Trial. Circulation. Published 29 August 2024. doi:10.1161/circulationaha.124.071208
Summarised from the published abstract; every number is checked against it