Arrhythmias & electrophysiologyCohort study

Return-to-Play for Elite Athletes With Genetic Heart Diseases Predisposing to Sudden Cardiac Death

J Am Coll CardiolPublished

  • Retrospective cohort study
  • multicentre

Authors' conclusion

After careful evaluation, risk stratification, and tailoring of their GHD therapy, RTP following SDM appears associated with low, nonfatal events rates at elite levels of sport.

Study context

Population
NCAA Division I university and professional athletes diagnosed with a genetic heart disease predisposing to sudden cardiac death (SCD)
Participants
76 participants
Outcome
Clinical outcomes: RTP outcomes and cardiac events

Main finding

As reported in the abstract

GHD-associated adverse cardiac events · mean follow-up 7 ± 6 years

Exercise-related GHD-associated adverse cardiac events

1 (1.3%)

Nonexercise-related GHD-associated adverse cardiac events

2

Observational data: associations, not effects.

Further findings

Initial disqualification followed by unrestricted return-to-play (RTP) after evaluation and shared decision making (SDM)

Initially disqualified, then opted for unrestricted RTP
55 of 76, 72%

Asymptomatic before diagnosis

Asymptomatic before diagnosis (GHD mostly detected at routine preparticipation CV screening)
48 of 76, 63%

Original publication

Return-to-Play for Elite Athletes With Genetic Heart Diseases Predisposing to Sudden Cardiac Death. J Am Coll Cardiol. Published 22 August 2023. doi:10.1016/j.jacc.2023.05.059

Summarised from the published abstract; every number is checked against it