Heart failure & cardiomyopathies
Right Ventricular Function on Cardiovascular Magnetic Resonance Imaging and Long-Term Outcomes in Stable Heart Transplant Recipients
Main finding · Death or MACEResult — go to the resultHazard ratio 1.08 95% CI 1.00–1.17Authors' conclusion
CMR feature tracking-derived RVGLS assessed at least 1 year after heart transplantation was independently associated with the long-term risk of death or major adverse cardiac events.
Study context
- Population
- Stable heart transplant recipients undergoing surveillance CMR at least 1 year after transplantation108 with death or MACE
- Participants
- 257 recipients
- Exposure
- Right ventricular (RV) function on CMR and long-term outcomes
- Outcome
- Composite of:
- Death
- MACE (retransplantation, nonfatal MI, coronary revascularization, HF hospitalization)
- Follow-up
- Median 4.4 years after CMR
Methodological detailsconsecutive recipients, multivariable Cox regression
- Consecutive recipients
- Multivariable Cox regression
Main finding
Death or MACE · median follow-up 4.4 years
Hazard ratio
1.08
95% CI 1.00–1.17
P = 0.046
RVGLS (per 1% worsening)
HR 1.08 (95% CI 1.00–1.17); P = 0.046
Per 1% worsening, as printed
As reported in the abstract
Observational data: associations, not effects.
Further findings
Death or MACE, subgroups with normal RVEF and with LGE imaging
- RV global longitudinal strain (RVGLS) association replicated
CV death or MACE
- Similar association with RVGLS
Original publication
Right Ventricular Function on Cardiovascular Magnetic Resonance Imaging and Long-Term Outcomes in Stable Heart Transplant Recipients. Circ Cardiovasc Imaging. Published 2 April 2024. doi:10.
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