Cardio-oncology & otherCohort study

Risk Factors and Temporal Trends of Maternal Heart Failure

JACC Heart FailPublished

  • Nationwide cohort study
  • national registers

Authors' conclusion

The increasing incidence of maternal HF in Sweden highlights a growing clinical concern.

Study context

Population
Deliveries to women without pre-existing cardiac disease, Swedish Medical Birth Register, 2000–2019
Participants
2,078,384 deliveries
Outcome
Annual incidence of maternal HF

Main finding

As reported in the abstract

Maternal HF incidence · 2000-2019

Overall incidence per 1,000 deliveries

0.34 (95% CI: 0.30-0.38)

Increase in maternal heart failure (HF) over the study period

66%

Observational data: associations, not effects.

Further findings

Associated cardiac disease

Present in approximately one-half of cases

Risk factors

Prepregnancy comorbidities and pregnancy complications identified as risk factors
Rising incidence partly, yet not fully, explained by changes in risk factor prevalence

Original publication

Risk Factors and Temporal Trends of Maternal Heart Failure. JACC Heart Fail. Published 25 August 2025. doi:10.1016/j.jchf.2025.102617

Summarised from the published abstract; every number is checked against it