Prevention & lipidsCohort study
Risk of suicide in individuals with atherosclerotic cardiovascular disease: a nationwide population-based study
- Population-based cohort study
- nationwide
- age- and sex-matched controls
Authors' conclusion
Individuals with ASCVD have increased risks of suicide.
Study context
- Population
- Korean National Health Insurance Service data; patients diagnosed with atherosclerotic cardiovascular disease (ASCVD) 2004–2008, followed until 20211,250 suicides
- Participants
- 37,912 vs 189,560
- Exposure
- ASCVD vs matched controls without ASCVD
- ASCVDn = 37,912
- Matched controlsn = 189,560reference
- Outcome
- Suicide
- Follow-up
- Median 11.3 years
Main finding
As reported in the abstract
Hazard ratio
1.43
95% CI 1.24–1.65
By group
ASCVD vs Matched controls
HR 1.43 (95% CI 1.24–1.65)
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| Suicide, by ASCVD type — MI vs Matched controls | 1.42 (1.14–1.78) | |
| Suicide, by ASCVD type — Stroke vs Matched controls | 1.47 (1.23–1.76) | |
| Suicide, by ASCVD type — Both MI and stroke vs Matched controls | 1.85 (1.07–3.21) | |
| 0.20.5125Hazard ratio (log scale) |
Suicide, by age, sex and history of depressive disorder (subgroups)
- Association consistent across age, sex, and history of depressive disorder
Original publication
Risk of suicide in individuals with atherosclerotic cardiovascular disease: a nationwide population-based study. Eur J Prev Cardiol. Published 6 January 2026. doi:10.1093/eurjpc/zwag013
Summarised from the published abstract; every number is checked against it