Prevention & lipidsDiagnostic or prognostic study
Risk Score Development to Predict Postpartum Cardiovascular Disease Incorporating Pregnancy and Nonpregnancy Factors
- Risk score development
- national administrative hospitalization data
- Cox proportional hazards models
Authors' conclusion
The lack of sociodemographic, clinical, and health behavior information may have contributed to the low predictive performance of this score for postpartum CVD hospitalizations. However, this score derived from a national administrative database, provides an initial framework for estimating future cardiac risk, which may provide guidance regarding the need and intensity of postpartum CVD surveillance.
Study context
- Population
- Individuals aged 18–55 years without pre-existing cardiovascular disease (CVD), 1 randomly selected delivery per individual, Canada 2008–2021cohort, median follow-up 3.7 years [Q1-Q3: 1.6–7.9 years]
- Participants
- 1,992,972 individuals
- Comparison
- standardized risk score <0 vs standardized risk score 0 to <3 vs standardized risk score ≥3
Performance
As reported in the abstract
standardized risk score <0
0.55
LR · 95% CI 0.49–0.61
standardized risk score 0 to <3
1.42
LR · 95% CI 1.28–1.57
standardized risk score ≥3
7.81
LR · 95% CI 6.69–9.11
Further findings
Distribution of risk scores
Model performance
- C-statistic for the multivariable Cox model
- 0.669 (95% CI: 0.668-0.670)
Original publication
Summarised from the published abstract; every number is checked against it