Arrhythmias & electrophysiologyRandomised controlled trial
Role of electroanatomical mapping–guided superior vena cava isolation in paroxysmal atrial fibrillation patients without provoked superior vena cava triggers: a randomized controlled study
- Randomised controlled trial
Authors' conclusion
Electroanatomical mapping-guided SVCI, in addition to CPVI, did not increase the success rate of PAF ablation in patients who had no identifiable SVC triggers.
Study context
- Population
- Patients undergoing paroxysmal AF ablation without provoked superior vena cava (SVC) triggers30 with SVC triggers, not randomised
- Participants
- 130 patients
- Comparison
- Circumferential pulmonary vein isolation (CPVI) plus SVCI vs CPVI only in paroxysmal atrial fibrillation (PAF) without provoked SVC triggers
- Primary endpoint
- Freedom from any documented atrial tachyarrhythmias >30 s after a 3-month blanking period without anti-arrhythmic drugs
- Follow-up
- 12 months after ablation
Primary result
As reported in the abstract
Freedom from atrial tachyarrhythmias · 12 months
CPVI plus SVCI
87.9
%
CPVI only
79.6%
P = 0.28
Further findings
Prevalence of SVC triggers in PAF
- SVC triggers identified
- 30 (23.1%)
Freedom from atrial tachyarrhythmias in patients with provoked SVC triggers (CPVI plus SVCI, non-randomised) · 12 months
- Free from atrial tachyarrhythmias
- 93.3%
Original publication
Role of electroanatomical mapping–guided superior vena cava isolation in paroxysmal atrial fibrillation patients without provoked superior vena cava triggers: a randomized controlled study. Europace. Published 2 February 2024. doi:10.1093/europace/euae039
Summarised from the published abstract; every number is checked against it