Arrhythmias & electrophysiology
Safety of ventricular arrhythmia radiofrequency ablation with half-normal saline irrigation
Authors' conclusion
Half-normal saline irrigation RF ablation with power guided by impedance fall and intracardiac echocardiography has an acceptable rate of complications and acute ablation success while administering half of the saline load expected for NS irrigation.
Study context
- Population
- Patients undergoing endocardial and/or epicardial radiofrequency (RF) ablation of ventricular arrhythmiasprocedures in 935 patients
- Participants
- 1,024 patients
- Exposure
- Half-normal saline vs normal saline irrigation for RF ablation
- Half-normal saline (HNS)n = 900
- Normal saline (NS)n = 124reference
- Outcome
- Periprocedural complications and acute ablation outcome
- Follow-up
- 30 days
Methodological detailsconsecutive patients, Irrigant selected at the discretion of the treating physician, RF power titrated to a ≤15 Ω impedance fall with intracardiac echocardiography monitoring
- Consecutive patients
- Irrigant selected at the discretion of the treating physician
- RF power titrated to a ≤15 Ω impedance fall with intracardiac echocardiography monitoring
Main finding
As reported in the abstract
Any adverse event
HNS
13.0%
Observational data: associations, not effects.
Safety
- Stroke/TIA (HNS) · 30 days
- 0.4% · 4 of 900
- Pericardial effusion requiring treatment (HNS) · 30 days
- 3.8% · 34 of 900
Steam pops with perforation requiring surgical repair
- Steam pops with perforation requiring surgical repair
- 2 (0.2%)
Original publication
Safety of ventricular arrhythmia radiofrequency ablation with half-normal saline irrigation. Europace. Published 17 February 2024. doi:10.
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