Arrhythmias & electrophysiologyDiagnostic or prognostic study

Sampling frequency has architecture-dependent effects on electrocardiogram deep learning classification: Convolutional neural networks are robust, whereas transformers benefit modestly

Heart RhythmPublished

  • Analysis of the PTB-XL dataset evaluating convolutional neural network (CNN) and Patch Transformer architectures at varying ECG sampling frequencies
  • multilabel classification of 5 diagnostic superclasses
  • 100, 300, and 500 Hz

Authors' conclusion

ECG sampling frequency had modest, architecture-dependent effects on deep learning classification performance. CNNs were robust across 100-500 Hz, whereas the Patch Transformer benefited incrementally from higher temporal resolution at greater computational cost. These findings support a task- and architecture-aware approach to ECG acquisition in resource-constrained settings.

Study context

Population
12-lead electrocardiograms (ECGs) from the PTB-XL dataseteligible 12-lead ECGs
Participants
15,000 participants
Comparison
ECG sampling frequency across CNN and Patch Transformer architectures

Performance

As reported in the abstract

Macro receiver operating characteristic area under the curve
Test or model100 Hz300 Hz500 Hz
CNN0.8950.8860.881
Patch Transformer0.8560.8640.877

Further findings

Computational cost (training time, memory use, inference latency)

Higher sampling frequencies increased computational cost for both architectures, with longer training times, greater memory use, and slower inference

Sensitivity and learning-curve analyses

Supported architecture-dependent trends across the tested configurations

Original publication

Sampling frequency has architecture-dependent effects on electrocardiogram deep learning classification: Convolutional neural networks are robust, whereas transformers benefit modestly. Heart Rhythm. Published 4 August 2026. doi:10.1016/j.hrthm.2026.07.045

Summarised from the published abstract; every number is checked against it