Rationale, design and prerandomization data for a cluster randomized trial to assess the effect of a digitally enabled quality improvement intervention on LDL-C control in established atherosclerotic cardiovascular disease patients: The SAPPHIRE-LDL trial
Study context
- Population
- Established atherosclerotic cardiovascular disease (ASCVD) patients in outpatient clinics from public or private hospitals or private practices
- Participants
- 28 clusters
- Planned comparison
- Digitally enabled multifaceted quality improvement (QI) intervention or routine practice
- Primary endpoint
- LDL-C
- Follow-up
- 06 months after the intervention period
Methodological detailsintention-to-treat, generalized estimating equations-GEE
- Intention-to-treat
- Generalized estimating equations-GEE
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Rationale, design and prerandomization data for a cluster randomized trial to assess the effect of a digitally enabled quality improvement intervention on LDL-C control in established atherosclerotic cardiovascular disease patients: The SAPPHIRE-LDL trial. Am Heart J. Published 3 February 2025. doi:10.
Summarised from the published abstract; every number is checked against it