Heart failure & cardiomyopathies
Sarcopenia Prognosis Using Dual-Energy X-Ray Absorptiometry and Prediction Model in Older Patients with Heart Failure
Authors' conclusion
Sarcopenia diagnosed using DEXA was associated with poor prognosis in older patients with HF; however, the prediction equations were not.
Study context
- Population
- Patients aged ≥65 years hospitalised for heart failure (HF); median age 83 years, 50.2% men
- Participants
- 269 patients
- Exposure
- Sarcopenia by DEXA vs by ASM prediction equations
- Outcome
- All-cause mortality
- Follow-up
- Median 690 days (IQR: 459-730)
Main finding
As reported in the abstract
All-cause mortality (54 patients [19.9%] died) · median follow-up 690 days
Hazard ratio (95% CI)P value
DEXA-sarcopeniaadjusted for pre-existing risk factors
2.33(1.26–4.31)
P = 0.007Predicted-sarcopeniaadjusted
1.68(0.87–3.25)
P = 0.123Anthropometric-sarcopeniaadjusted
1.64(0.86–3.12)
P = 0.132Observational data: associations, not effects.
Further findings
Prevalence of sarcopenia
Original publication
Sarcopenia Prognosis Using Dual-Energy X-Ray Absorptiometry and Prediction Model in Older Patients with Heart Failure. ESC Heart Fail. Published 11 January 2024. doi:10.
Summarised from the published abstract; every number is checked against it