Prevention & lipidsCross-sectional study
SCORE2 charts assign a different risk category than the underlying model in a large portion of Polish primary care patients
- Cross-sectional study
- multicentre
- primary care
Authors' conclusion
SCORE2/SCORE2-OP charts tend to overestimate cardiovascular risk relative to the core risk models.
Study context
- Population
- Polish primary care patients from 16 regions, excluding very high-risk comorbidities or risk parameters exceeding permitted values
- Participants
- 6,621 patients
- Exposure
- SCORE2/SCORE2-OP charts vs SCORE2/SCORE2-OP model equations
Main finding
As reported in the abstract
Chart vs model risk estimate and category
- Chart estimate ≥20% higher than model
- 2,164 (32.7%)
- Chart estimate 20% lower than model
- 382 (5.6%)
- Assigned risks differed (Wilcoxon rank test)
- p<0.0001
- Chart assigned higher risk category
- 1,277 (19.3%)
- Chart assigned lower risk category
- 122 (1.8%)
- Category difference (McNemar-Bowker test)
- p<0.001
Observational data: associations, not effects.
Further findings
Pattern of chart-model difference
- Saw-tooth pattern across SBP, age and non-HDL; bias towards overestimation at higher HDL
Original publication
SCORE2 charts assign a different risk category than the underlying model in a large portion of Polish primary care patients. Eur J Prev Cardiol. Published 31 August 2025. doi:10.1093/eurjpc/zwaf555
Summarised from the published abstract; every number is checked against it