Cardio-oncology & otherMeta-analysis
Screening for Hypertensive Disorders of Pregnancy
- Systematic review
- targeted systematic review
- no quantitative synthesis
Authors' conclusion
This review did not identify evidence that any alternative screening strategies for hypertensive disorders of pregnancy were more effective than routine blood pressure measurement at in-person prenatal visits.
Study context
- Population
- Pregnant or postpartum individuals6 studies (5 trials, 1 nonrandomized)
- Participants
- 10,165 participants
- Comparison
- Alternative prenatal screening strategies vs usual care
- Home blood pressure measurementn = 2,521
- Reduced prenatal visit schedulesn = 5,203
- Proteinuria screeningn = 2,441
- Outcome
- Morbidity or mortality, measures of health-related quality of life
Pooled result
As reported in the abstract
Maternal and infant complications
- No statistically significant differences in maternal and infant complications with alternate strategies vs usual care; estimates imprecise for serious, rare outcomes
- no quantitative synthesis
Further pooled results
| Outcome | Home blood pressure measurement | Reduced prenatal visit schedules | Proteinuria screening | Usual care |
|---|---|---|---|---|
| Time to diagnosis of a hypertensive disorder of pregnancy (home BP measurement) | Not reported in the abstract | Not reported in the abstract | Not reported in the abstract | 106.2 days |
- Time to diagnosis of a hypertensive disorder of pregnancy (home BP measurement): Home BP measurement 104.3 days
Time to diagnosis of a hypertensive disorder of pregnancy (home BP measurement)
- Not associated with earlier diagnosis
Incidence of hypertensive disorders of pregnancy (reduced visit schedules)
- Incidence not different between groups in 3 trials
Postpartum screening for new-onset hypertensive disorders
- No studies addressed screening in the postpartum period
Safety
Harms of screening strategies
- No harms of the different screening strategies were identified
- 1 additional trial (n = 80) addressed harms of home BP measurement only
Original publication
Screening for Hypertensive Disorders of Pregnancy. JAMA. Published 19 September 2023. doi:10.1001/jama.2023.4934
Summarised from the published abstract; every number is checked against it