Cardio-oncology & otherCohort study
Severe Maternal Morbidity According to Mode of Delivery Among Pregnant Patients With Cardiomyopathies
- Retrospective cohort study
- target trial emulation
Authors' conclusion
In patients with cardiomyopathies, a trial of labor does not confer a higher risk of maternal morbidity, blood transfusion, or readmission compared with planned cesarean delivery.
Study context
- Population
- Pregnant patients with a cardiomyopathy, Premier inpatient administrative database
- Participants
- 2,921 deliveries
- Exposure
- Intended vaginal delivery vs intended cesarean delivery
- Outcome
- Nontransfusion severe maternal morbidity during delivery hospitalization, blood transfusion and readmission
Main finding
As reported in the abstract
Intended vaginal delivery vs Intended cesarean deliveryAdjusted odds ratio (95% CI)
nontransfusion morbidity
1.17(0.91–1.51)
blood transfusion
1.27(0.81–1.98)
readmission
1.03(0.73–1.44)
Observational data: associations, not effects.
Further findings
| Outcome | aOR (95% CI) | |
|---|---|---|
| Nontransfusion morbidity and blood transfusion, cesarean vs vaginal delivery (as-treated) — Cesarean delivery vs Vaginal delivery · nontransfusion morbidity · as-treated | 2.44 (1.85–3.22) | |
| Nontransfusion morbidity and blood transfusion, cesarean vs vaginal delivery (as-treated) — Cesarean delivery vs Vaginal delivery · blood transfusion · as-treated | 2.26 (1.34–3.81) | |
| 0.20.5125Adjusted odds ratio (log scale) |
Original publication
Severe Maternal Morbidity According to Mode of Delivery Among Pregnant Patients With Cardiomyopathies. JACC Heart Fail. Published 8 November 2023. doi:10.1016/j.jchf.2023.09.012
Summarised from the published abstract; every number is checked against it