Severe obesity in patients with ST-elevation myocardial infarctions: association with age, temporal trends, and clinical outcomes
Authors' conclusion
The significant increase in the prevalence of severe obesity among patients with STEMI, particularly among females and younger individuals
Study context
- Population
- Consecutive ST-elevation myocardial infarction (STEMI) patients admitted to a German heart centre, 2006–2022, in 5 WHO body mass index (BMI) groups
- Participants
- 11,629 patients
- Exposure
- Severe obesity vs normal weight
- Severe obesityn = 269
- Outcome
- Prevalence of severe obesity (BMI ≥ 40 kg/m²) in STEMI; association with age, temporal trends and outcomes
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
Prevalence of severe obesity
Severe obesity
2.3%
269 of 269
Observational data: associations, not effects.
Further findings
Age · younger on average
difference 8.6 · P < 0.01
| Outcome | Severe obesity | Normal weight | Adjusted HR (95% CI) | P value | |
|---|---|---|---|---|---|
| 30-day mortality | 14.2% | 9.2% | 1.99 (1.4–3.0) | P < 0.01 | |
| 5-year mortality | 30.6% | 20.6% | 2.03 (1.4–2.9) | P < 0.01 | |
| 0.20.5125Adjusted hazard ratio (log scale) |
Age
- Severe obesity more likely female and diabetic
Prevalence trend of severe obesity, 2006-13 vs 2013-22
- Overall
- 1.9 to 2.6%, P = 0.014
- Females
- 2.5-3.7%, P = 0.052
- Females <55 years (+128%)
- 4.9-11.3%, P < 0.01
- Men <55 years (+71%)
- 2.2-3.7%, P < 0.01
Treatment outcomes and in-hospital adverse events
- Not affected by severe obesity
Original publication
Severe obesity in patients with ST-elevation myocardial infarctions: association with age, temporal trends, and clinical outcomes. Eur J Prev Cardiol. Published 31 July 2025. doi:10.
Summarised from the published abstract; every number is checked against it