Heart failure & cardiomyopathies

Sex Differences in Clinical Characteristics, Treatment, and Outcomes of Cardiovascular Disease: Kenya Heart Registry Analysis

JACC AdvPublished Prospective registry study

Authors' conclusion

Significant sex differences exist in clinical profiles, but management and outcomes are similar.

Study context

Population
Patients with HF, ACS, VTE or AF in the Kenya Heart Registry51.3% women
Participants
1,687 patients
Exposure
Women vs men
Outcome
In-hospital and 6-month mortality, and sex-specific differences in clinical presentation, CV risk factors, diagnosis and treatment
Follow-up
In-hospital and 6 months
Methodological details3 tertiary hospitals, 1,241 admitted, 446 managed as outpatients
  • 3 tertiary hospitals
  • 1,241 admitted, 446 managed as outpatients

Main finding

As reported in the abstract

All-cause mortality

In-hospital mortality

P = 0.449

6-month mortality

P = 0.881

Overall in-hospital mortality
7.4%
Overall 6-month mortality
14.7%

Observational data: associations, not effects.

Further findings

Age

P < 0.001

Age

Women had lower monthly income, higher LVEF, higher rates of HFpEF, VTE and AF, and lower rates of ACS than men

Original publication

Sex Differences in Clinical Characteristics, Treatment, and Outcomes of Cardiovascular Disease: Kenya Heart Registry Analysis. JACC Adv. Published 19 December 2025. doi:10.1016/j.jacadv.2025.102466

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.