Sex Disparities in Ischemic Heart Disease Mortality in Europe
Authors' conclusion
Mortality from IHD has decreased substantially among EU countries. However, the declines were accompanied by a persistently higher ASMR-to-ASPR index in women, indicating significant potential for further gains in closing the gender gap in IHD mortality.
Study context
- Population
- Population of European Union (EU) countries with ischemic heart disease (IHD), 2005–2019
- Exposure
- Women vs men
- Outcome
- Sex-specific ASMR-to-ASPR index (age-standardized mortality rate to age-standardized prevalence rate ratio)
- Follow-up
- 2005 to 2019
Methodological detailsGlobal Burden of Disease Study Database, EU 2005–2019
- Global Burden of Disease Study Database
- EU 2005–2019
Main finding
As reported in the abstract
ASMR-to-ASPR index (EU average)
Ranging from 1.05 to 1.44; disparities persisted
Observational data: associations, not effects.
Further findings
| Outcome | Women | Men |
|---|---|---|
| ASMR, 2005 to 2019 | ||
| ASMR change | from 1.752 to 1.662 | from 3.372 to 3.135 |
Age-standardized mortality rate (ASMR), 2005 to 2019
- Men showed higher ASMR than women; significant decline in ASMR across EU in both sexes
Relationship of country-specific ASMR or country income status with ASMR-to-ASPR index
- No significant relationship
Country examples: Romania vs Germany
- Romania ASMR, men
- 219.87
- Romania ASMR, women
- 143.54
- Germany ASMR, men
- 107.22
- Germany ASMR, women
- 60.76
- Romania ASMR-to-ASPR index, women vs men
- 6.54% vs 5.85%
- Romania women-to-men ratio
- 1.12
- Germany ASMR-to-ASPR index, women vs men
- 4.79% vs 3.80%
- Germany women-to-men ratio
- 1.26
Original publication
Sex Disparities in Ischemic Heart Disease Mortality in Europe. JACC Adv. Published 2 September 2024. doi:10.
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