Coronary disease & ACSMeta-analysis
Sex influence on in-hospital and long-term prognosis of myocardial infarction with non-obstructive coronary artery disease: a systematic review and meta-analysis
- Systematic review and meta-analysis
Authors' conclusion
Sex does not seem to influence MINOCA prognosis, except for a higher incidence of stroke during follow-up found in women. In females, MINOCA has lower in-hospital mortality than MI-CAD.
Study context
- Population
- Patients with MI with non-obstructive coronary artery disease (MINOCA)
- Participants
- 42,870 patients · 15 studies
- Comparison
- Men vs women with MINOCA
- Womenn = 25,172reference
- Outcome
- Overall mortality and major adverse cardiovascular events (MACE) during hospitalization and at follow-up
Pooled result
As reported in the abstract
In-hospital mortality and all-cause death at follow-up, by sex
No sex difference in in-hospital mortality
OR: 1.05; 95% CI: 0.82-1.34; I2 = 0%
No sex difference in all-cause death at follow-up
OR: 0.93; 95% CI: 0.76-1.13; I2 = 54%
Further pooled results
| Outcome | OR (95% CI) | |
|---|---|---|
| In-hospital mortality, MINOCA vs MI-CAD (women) · women; I2 = 70% | 0.39 (0.21–0.72) | |
| 0.20.5125Odds ratio (log scale) |
In-hospital mortality, MINOCA vs MI-CAD (women)
- No relevant differences in males
Original publication
Sex influence on in-hospital and long-term prognosis of myocardial infarction with non-obstructive coronary artery disease: a systematic review and meta-analysis. Eur J Prev Cardiol. Published 5 August 2025. doi:10.1093/eurjpc/zwaf495
Summarised from the published abstract; every number is checked against it